Gene interactions and pathways from curated databases and text-mining

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EPHB2 — LRRC4

Text-mined interactions from Literome

Zhang et al., FEBS Lett 2005 (Brain Neoplasms) : Results showed that LRRC4 induced a cell cycle delay at the late G1 phase, probably through the alteration of the expression of different cell cycle regulating proteins responsible for mediating G1-S progression, such as p21 ( Waf1/Cip1 ) and p27 ( Kip1 ), Cdk2 and PCNA, p-ERK1/2
Wu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 (Glioma...) : LRRC4 down-regulated the expression of phosphorylated ERK2 and up-regulated the expression of total protein JNK2 ( a key molecule of MAPK signaling pathway ) and phosphorylated c-Jun