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BDNF — CA2
Text-mined interactions from Literome
Tabuchi et al., J Biol Chem 2000
(Calcium Signaling) :
Differential
activation of
brain derived neurotrophic factor gene promoters I and III by
Ca2+ signals evoked via L-type voltage dependent and N-methyl-D-aspartate receptor Ca2+ channels
Mizoguchi et al., Eur J Neurosci 2002
(Calcium Signaling...) :
Brain derived neurotrophic factor (BDNF) increases postsynaptic intracellular
Ca2+ and modulates synaptic transmission in various types of neurons
Kingsbury et al., J Biol Chem 2003
:
The coordinated
regulation of
BDNF and trkB by
Ca2+ may play a role in activity dependent survival and synaptic plasticity by enhancing BDNF signaling in electrically active neurons
Mizoguchi et al., Neuroreport 2003
:
BDNF increased intracellular
Ca2+ through the PLC-gamma phosphorylation after the TrkB receptor tyrosine kinase activation
Poulsen et al., Neuroscience 2004
(Seizures) :
Activity dependent
brain derived neurotrophic factor (BDNF) expression is
Ca2+ dependent , yet little is known about the Ca2+ channel contributions that might direct selective expression of the multiple BDNF transcripts
Li et al., Nature 2005
(Calcium Signaling) :
The BDNF induced chemo-attraction of axonal growth cones requires Ca2+ signalling, but how
Ca2+ is
regulated by
BDNF at the growth cone remains largely unclear
Yagasaki et al., J Biol Chem 2006
:
We found that the
BDNF stimulated PLC-gamma activation and the ensued increase in intracellular
Ca2+ ( [ Ca2+ ] i ) were potentiated by pretreatment with imipramine or fluvoxamine, so was the BDNF induced glutamate release
Jia et al., Nat Neurosci 2007
:
In CGN cultures, blocking TRPC channels or downregulating TRPC3 or 6 suppressed brain derived neurotrophic factor (BDNF) mediated protection, BDNF triggered intracellular
Ca2+ elevation and
BDNF induced CREB
activation
Zheng et al., J Neurochem 2008
(Ion Channel Gating) :
Interestingly, sub-nanomolar
BDNF did not
stimulate [
Ca2+ ] i increase under our culture conditions
McGurk et al., J Neurosci 2011
(Synaptic Transmission) :
Functionally, XTRPC1 was required specifically in postsynaptic myocytes for
BDNF induced
Ca2+ elevation and full synaptic potentiation at the NMJ, suggesting a previously underappreciated postsynaptic function of Ca2+ signaling in neurotrophin induced synaptic plasticity, in addition to its well established role at presynaptic sites
Marsh et al., J Neurochem 1996
:
The
effects of both NT-3 and
BDNF on
Ca2+ levels were attenuated in Ca ( 2+ ) -free medium, suggesting that both neurotrophins increase Ca2+ flux across the plasma membrane as well as release from internal stores
Tao et al., Neuron 1998
:
This report describes experiments demonstrating that CREB or a closely related protein mediates
Ca2+ dependent regulation of
BDNF , a neurotrophin that modulates synaptic activity