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IFNA2 — VEGFA
Text-mined interactions from Literome
Fukuda et al., Fertil Steril 2004
(Choristoma) :
Differential
effects of
interferon-alpha and -beta on the secretion of
vascular endothelial growth factor by eutopic and ectopic endometrial stromal cells
Wu et al., J Cancer Res Clin Oncol 2005
(Carcinoma, Hepatocellular...) :
Blocking the function of IFN-alpha receptor with a specific peptide could eliminate the inhibitory
effects of
IFN-alpha 2a on
VEGF expression ... These observations may lead to the conclusion that
IFN-alpha 2a could
suppress VEGF synthesis and secretion by down regulating HIF-1 alpha expression, via inhibition of the PI3 kinase and/or the MAP kinase signaling pathways
Raig et al., J Interferon Cytokine Res 2008
(Melanoma...) :
VEGF secretion is
inhibited by
interferon-alpha in several melanoma cell lines
Cao et al., World J Gastroenterol 2008
(Carcinoma, Hepatocellular...) :
Inhibitory
effect of
interferon-alpha-2b on expression of cyclooxygenase-2 and
vascular endothelial growth factor in human hepatocellular carcinoma inoculated in nude mice ... To evaluate the
effects of
interferon-alpha-2b ( IFN-alpha-2b ) on expression of cyclooxygenase-2 (COX-2) and
vascular endothelial growth factor ( VEGF ) in human hepatocellular carcinoma ( HCC ) inoculated in nude mice and to study the underlying mechanism of IFN-alpha-2b against HCC growth
Zhang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2010
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive...) :
The
IFN-alpha2b displays anti-angiogenesis by inhibiting the proliferation, migration and tubule formation in vitro of HUVEC and down
regulating the expression of
VEGF and bFGF mRNA