Gene interactions and pathways from curated databases and text-mining

◀ Back to E2F1

E2F1 — POLDIP2

Text-mined interactions from Literome

Hershko et al., J Biol Chem 2006 : We show here that E2F1 modulates the activity of the p38 MAPK pathway via E2F1 induced transient up-regulation of p38 MAPK phosphorylation
de Olano et al., Mol Cancer Res 2012 : Consistently, studies using pharmacologic inhibitors, siRNA knockdown, and knockout mouse embryonic fibroblasts (MEF) revealed that p38 mediates the E2F1 induction by epirubicin and that the induction of E2F1 by p38 is, in turn, mediated through its downstream kinase MK2 [ mitogen activated protein kinase ( MAPK) activated protein kinase 2 ; MAPKAPK2 ]