◀ Back to CTNNB1
CTNNB1 — HNF1A
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin (CTNNB1)
→
CtBP/CBP/TCF1/TLE1/AES complex (CTBP1-CREBBP-HNF1A-TLE1-AES)
(modification, collaborate)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin (CTNNB1)
→
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
(modification, collaborate)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
CtBP/CBP/TCF1/TLE1/AES complex (CTBP1-CREBBP-HNF1A-TLE1-AES)
→
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
(modification, collaborate)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
Nemo like kinase (NLK)
→
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
(modification, inhibits)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
CtBP/CBP/TCF1/TLE1/AES complex (CTBP1-CREBBP-HNF1A-TLE1-AES)
(transcription, activates)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
MYC (MYC)
(transcription, activates)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
CtBP/CBP/TCF1/TLE1/AES complex (CTBP1-CREBBP-HNF1A-TLE1-AES)
(transcription, activates)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
Cyclin D1 (CCND1)
(transcription, activates)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
CtBP/CBP/TCF1/TLE1/AES complex (CTBP1-CREBBP-HNF1A-TLE1-AES)
(transcription, activates)
-
NCI Pathway Database Presenilin action in Notch and Wnt signaling:
beta catenin/TCF1/CtBP/CBP/TLE1/AES/SMAD4 complex (CTNNB1-HNF1A-CTBP1-CREBBP-TLE1-AES)
→
PPAR delta (PPARD)
(transcription, activates)
-
WikiPathways ESC Pluripotency Pathways:
CTNNB1
→
HNF1A/CTNNB1
(activation)
-
WikiPathways Role of Osx and miRNAs in tooth development:
SOST
→
Complex of HNF1A-CTNNB1
(mim-inhibition)
-
WikiPathways Role of Osx and miRNAs in tooth development:
DKK1
→
Complex of HNF1A-CTNNB1
(mim-inhibition)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Staal et al., Int Immunol 1999
:
Here we report that in T cells,
Tcf-1 also becomes transcriptionally
active through interaction with
beta-catenin , suggesting that the Wnt signal transduction pathway is operational in T lymphocytes as well
Jeannet et al., Proc Natl Acad Sci U S A 2010
:
The function of
Tcf-1 to establish CD8 T cell memory is dependent on the catenin binding domain in Tcf-1 and
requires the Tcf-1 coactivators and Wnt signaling intermediates
beta-catenin and gamma-catenin