Gene interactions and pathways from curated databases and text-mining

◀ Back to ARF6

ARF6 — VEGFA

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Complex of ARF6-RAC1 → VEGFA (increases)
    Evidence: In ECs, VEGF stimulates ARF6 association with Rac1, which is cotemporaneous with Rac1 activation.

Text-mined interactions from Literome

Martin et al., Invest Ophthalmol Vis Sci 2004 (Eye Abnormalities...) : In the HVS, Arf expression in perivascular cells may block their accumulation or repress Vegf expression to promote HVS involution and prevent PHPV
Ikeda et al., Circ Res 2005 (Ischemia) : Thus, ARF6 is involved in the temporal-spatial organization of caveolae/lipid rafts- and ROS dependent VEGF signaling in ECs as well as in angiogenesis in vivo