◀ Back to JUN

JUN — SAG

Text-mined interactions from Literome

Kim et al., Neurosci Lett 2007 (Neuroblastoma...) : Furthermore, SAG inhibits MEKK1 dependent c-Jun transcription activity in SH-SY5Y cells
Gu et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : When overexpressed, SAG remarkably reduced both basal and TPA induced c-Jun levels, whereas SAG small interfering RNA ( siRNA ) silencing increased substantially the levels of both basal and TPA induced c-Jun ... Thus, AP-1/SAG establishes an autofeedback loop, in which on induction by AP-1, SAG promotes c-Jun ubiquitination and degradation, thus inhibiting tumor promoting activity of AP-1