Burry et al., J Histochem Cytochem 2006
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Stimulation of PC12 cells with NGF induces neuronal differentiation including outgrowth of neurites and increased levels of GAP-43 protein, whereas HuD remains localized in small cytoplasm granules and is still present in the nucleus
Fukao et al., Mol Cell 2009
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The RNA binding protein HuD promotes neuronal differentiation by an unknown mechanism ... This example of cap dependent translational regulation might explain at least in part how HuD triggers the induction of neuronal differentiation Joseph et al., J Biol Chem 1998
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The neuronal members of this family ( HuD , HuC, and Hel-N1 ) are required for neuronal differentiation