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BCL2 — GLI2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Innatedb Interaction: Complex of GLI2-BCL2-GLI2 (unknown, -) Kurita et al., PloS one 2011*
• IRef Innatedb Interaction: BCL2 — GLI2 (unknown, -) Regl et al., Cancer Res 2004*

Text-mined interactions from Literome

Kump et al., Oncogene 2008 (Carcinoma, Basal Cell) : As cFlip and Bcl-2 are highly expressed in BCCs, as a consequence of high Gli2 expression, this may explain the marked resistance of the tumor to the extrinsic and intrinsic apoptotic pathway
Mazumdar et al., Cancer Res 2011 (Carcinoma...) : GANT61 specifically targeted Gli1 and Gli2 substantiated by specific inhibition of ( i ) direct binding of Gli1 and Gli2 to the promoters of target genes HIP1 and BCL-2, ( ii ) Gli-luciferase activity, and ( iii ) transcriptional activation of BCL-2