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CCND1 — NCOA3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CCND1 — NCOA3 (physical association, affinity chromatography technology) Zwijsen et al., Genes Dev 1998*
• IRef Hprd Interaction: CCND1 — NCOA3 (in vivo) Zwijsen et al., Genes Dev 1998*
• IRef Innatedb Interaction: Complex of ESR1-CCND1-CHUK-NCOA3 (unknown, -) Park et al., Mol Cell 2005
• IRef Innatedb Interaction: NCOA3 — CCND1 (unknown, -) Park et al., Mol Cell 2005
• IRef Ophid Interaction: NCOA3 — CCND1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Planas-Silva et al., Cancer Res 2001 (Breast Neoplasms) : AIB1 enhances estrogen dependent induction of cyclin D1 expression
Roy et al., Journal of molecular signaling 2010 : SFN induced the expression of p21/CIP1 and p27/KIP1, and inhibited the expression of cyclin D1
Roy et al., PloS one 2011 (Pancreatic Neoplasms) : Resveratrol induced cell cycle arrest by up-regulating the expression of p21/CIP1 , p27/KIP1 and inhibiting the expression of cyclin D1
Chen et al., Gut 2013 (Carcinoma, Hepatocellular...) : Cell line studies showed that metformin inhibits hepatocyte proliferation and induces cell cycle arrest at G0/G1 phase via AMP activated protein kinase and its upstream kinase LKB1 to upregulate p21/Cip1 and p27/Kip1 and downregulate cyclin D1 in a dose dependent manner, but independent of p53