Gene interactions and pathways from curated databases and text-mining

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CHI3L1 — IL8

Text-mined interactions from Literome

Ling et al., Biochem J 2004 (Inflammation) : HC-gp39 suppressed the cytokine induced secretion of MMP1, MMP3 and MMP13, as well as secretion of the chemokine IL-8
Chen et al., Clin Immunol 2011 : Downstream, CHI3L1 enhanced the secretion of IL-8 and TNFa in a dose dependent manner
Tang et al., J Immunol 2013 (Asthma...) : YKL-40 induced IL-8 was found to further stimulate proliferation and migration of BSMCs, and the effects were inhibited after neutralizing IL-8