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GNRH1 — SCG2

Text-mined interactions from Literome

Nicol et al., J Endocrinol 2002 : These results indicate that there is a close correlation between the GnRH stimulated release of LH and SgII from LbetaT2 cells, suggesting that SgII may have an influential role in the regulated secretion of LH, possibly by inducing LH aggregation to facilitate trafficking into secretory granules
Song et al., Mol Cell Endocrinol 2003 : DNA between -91 and -60 relative to the transcription start site was found to be required for GnRH induced SgII reporter gene activation ... These studies offer evidence that GnRH induced activation of the SgII promoter in the alphaT3-1 cell line requires cAMP dependent protein kinase activity and a functional CRE within the 5'-flanking region of the gene
Samia et al., Gen Comp Endocrinol 2004 : We investigated the effects of different sex steroids on pituitary SgII expression throughout the seasonal reproductive cycle of the female goldfish, as well as the effects of GnRH and testosterone on pituitary LHbeta subunit, GH, and SgII expression in sexually recrudescent female fish using northern blot analysis ... Although testosterone alone did not alter the expression of either of these genes, it did abolish the stimulatory effects of GnRH on both LHbeta and SgII expression
Xie et al., Endocrinology 2008 (MAP Kinase Signaling System) : Previous studies demonstrated that GnRH induced secretogranin II (SgII) promoter regulation required a consensus cAMP response element ( CRE ) and protein kinase A/CRE binding protein
Vasauskas et al., Gen Comp Endocrinol 2011 : The squirrel monkey and human SgII promoters were similarly activated by GnRH in luciferase reporter gene assays in LßT2 cells