Gene interactions and pathways from curated databases and text-mining

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GNRH1 — SP1

Text-mined interactions from Literome

Zeng et al., Exp Clin Endocrinol Diabetes 2005 : Signal transduction mediating gene expression of SP1 , LHbeta-subunit and GH in response to GnRH or GHRH in the postnatal and fetal porcine anterior pituitary in vitro ... Postnatally ( 4 weeks ) SP1 mRNA level was maximally increased by GnRH , GHRH and both by activation of AC or PKC after 2 h of exposure
Kaiser et al., J Biol Chem 1998 : Sp1 binds to the rat luteinizing hormone beta ( LHbeta ) gene promoter and mediates gonadotropin releasing hormone stimulated expression of the LHbeta subunit gene