◀ Back to AKT3

AKT3 — HOXD13

Text-mined interactions from Literome

Zhang et al., Neurosci Lett 2005 : Here, we report that SPD prevented neuronal cell death from H2O2 exposure and increased the levels of phosphorylated Akt ( pAkt ), a serine/threonine protein kinase ... The SPD induced neuroprotection and activation of Akt were blocked by LY294002, a PI3-K inhibitor, suggesting that the anti-apoptotic action of SPD is mediated via the PI3-K/Akt signaling pathway
Yang et al., Oxidative medicine and cellular longevity 2013 : In conclusion, these results suggest that SPD induces PI3K/Akt-Nrf2 mediated HO-1 expression in human endothelial cells, which may have a role in cytoprotection of the cells against oxidative stress induced death