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EGFR — PXN
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Salazar et al., J Cell Physiol 2003
:
The experiments presented here were designed to test the
role of
epidermal growth factor receptor (EGFR) transactivation in the rapid increase of tyrosine phosphorylation of FAK and
paxillin induced by GPCR agonists
Marcoux et al., Cell Signal 2005
:
We demonstrate here that integrin dependent
EGFR activation is also
essential for adhesion induced formation of actin stress fibers, focal adhesion localization and tyrosine phosphorylation of the adapter protein
paxillin , as well as transcriptional activation of the serum response factor
Sen et al., J Biol Chem 2010
(MAP Kinase Signaling System...) :
Furthermore,
EGFR induced Erk activation
requires Src mediated phosphorylation of
paxillin on tyrosines 31/118