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EPHB2 — ITGA6

Text-mined interactions from Literome

Ferletta et al., Mol Biol Cell 2003 : The ERK activation was mediated by integrin alpha6beta1 and not by alpha3beta1 or dystroglycan ... Instead, we found that dystroglycan binding domains of both laminin-1 and -10/11 suppressed integrin alpha6beta1 mediated ERK activation ... We conclude that laminin-1 and -10/11 share the ability to induce ERK activation, that this is regulated by integrin alpha6Abeta1 , and suggest a novel role for dystroglycan binding laminin domains as suppressors of this activation
Joly et al., J Biol Chem 2006 (Kidney Diseases, Cystic...) : Ligation of alpha(6)beta(4) integrin , a major Ln-5 receptor aberrantly expressed by ADPKD cells, induces beta ( 4 ) integrin phosphorylation, ERK activation, cell proliferation, and cyst formation