Gene interactions and pathways from curated databases and text-mining

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BNIP3 — MYLIP

Text-mined interactions from Literome

Chen et al., Cancer Res 2010 (Adenocarcinoma...) : Although BNIP3 transcription is controlled by hypoxia-inducible factor 1alpha ( also elevated in prostate cancer ), we postulated the posttranscriptional regulation of BNIP3 by miR145 through bioinformatics analysis, and herein we experimentally showed that miR145 negatively regulated BNIP3 by targeting its 3'-untranslated region
Wang et al., Stem cell research 2013 : Following the identification of the miR-210 putative target genes, we demonstrated that the Bcl-2 adenovirus E1B 19kDa interacting protein 3 (BNIP3) , which is regulated by HIF-1 and activates cell death, is regulated by miR-210 in NPCs under hypoxia ... The upregulation of miR-210 then directly suppresses BNIP3 expression to maintain the survival of NPCs under hypoxia