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IL15 — IL7

Text-mined interactions from Literome

Ogata et al., J Immunol 1999 : Although IL-15 is known as a potent stimulator of TNF-alpha, its activity was not abolished by addition of anti-TNF-alpha Ab. Interestingly, IL-2 and IL-7 , which utilize some IL-15R components, had no effect on osteoclast differentiation, but pretreatment with IL-2 or IL-7 of bone marrow cells before the addition of IL-15 inhibited the enhancing activity of IL-15
D'Agostino et al., Scand J Immunol 2004 (Leishmaniasis, Visceral) : Interleukin-15 , as interferon-gamma, induces the killing of Leishmania infantum in phorbol-myristate-acetate activated macrophages increasing interleukin-12
Surh et al., Semin Immunol 2005 : In essence, homeostasis of naïve T cells is regulated by IL-7 and self-MHC/peptide ligands and homeostasis of memory CD8 cells is controlled by IL-7 and IL-15
Liu et al., J Immunother 2006 : IL-7 alone did not induce significant proliferation of any tumor-reactive T-cell population, whereas IL-2 and IL-15 induced significant proliferation of tumor-reactive T lymphocytes from both sources
Quinci et al., Eur J Immunol 2012 : IL-15 inhibits IL-7Ra expression by memory-phenotype CD8? T cells in the bone marrow