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CBFA2T2 — CD28
Text-mined interactions from Literome
Taylor et al., Immunology 2006
:
IL-10 inhibits
CD28 tyrosine phosphorylation,
preventing the binding of phosphatidylinositol 3-kinase
p85 and consequently inhibiting the CD28 signalling pathway
Alcázar et al., Blood 2009
:
Considering that p85beta-deficient T cells fail in recall responses and that
p85beta binds to and
regulates CD28 signals, the presented observations suggest the involvement of p85beta in CD28 mediated activation and differentiation of antigen stimulated T cells