Gene interactions and pathways from curated databases and text-mining

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CBFA2T2 — CD28

Text-mined interactions from Literome

Taylor et al., Immunology 2006 : IL-10 inhibits CD28 tyrosine phosphorylation, preventing the binding of phosphatidylinositol 3-kinase p85 and consequently inhibiting the CD28 signalling pathway
Alcázar et al., Blood 2009 : Considering that p85beta-deficient T cells fail in recall responses and that p85beta binds to and regulates CD28 signals, the presented observations suggest the involvement of p85beta in CD28 mediated activation and differentiation of antigen stimulated T cells