Gene interactions and pathways from curated databases and text-mining

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JAK3 — MMP13

Text-mined interactions from Literome

El Mabrouk et al., Biochim Biophys Acta 2007 : These results suggest that OSM stimulated ADAMTS-4 and MMP-13 expression is mediated by ERK1/2, JAK3/STAT1/3 and PI3K/Akt and by cross talk between these pathways
Huang et al., Rheumatology (Oxford) 2011 (Osteoarthritis) : Both janus kinase 2 (JAK2) and JAK3 inhibitors suppressed AGE induced MMP-13 , ADAMTS-4 and ADAMTS-5 expression and enzyme activity