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AD5 — IL6

Text-mined interactions from Literome

Jijon et al., Cell Signal 2004 : Functional analysis demonstrated that Ad5NIK induced NF-kappaB transcriptional activity, IL-6 mRNA expression and RelA phosphorylation are inhibited by the p38 inhibitor SB203580, suggesting a role for this MAPK in NIK signaling to NF-kappaB
Matkovic et al., J Cell Physiol 2009 (Adrenal Cortex Neoplasms...) : Both AdVs and Ad5WT induced expression of inflammatory cytokines, such as interleukin-6 and tumor necrosis factor-alpha, but, most importantly, they led to a marked and dose dependent increase of cortisol and other steroid hormone production and consistently modulated expression of key steroidogenic enzymes and regulators of steroidogenesis