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MMP26 — SPP1
Text-mined interactions from Literome
Lai et al., Circ Res 2006
:
To better understand its role in vascular remodeling, we assessed how
OPN controls metalloproteinase (
MMP ) activation in aortic adventitial myofibroblasts ( AMFs ) and A7r5 vascular smooth muscle cells ( VSMCs )
Castellano et al., Clin Cancer Res 2008
(Disease Progression...) :
Osteopontin (OPN) , which
activates matrix metalloproteinases ( MMP ) , is considered a prognostic biomarker in several cancers ... `` In silico '' and experimental approaches were used to determine whether
OPN mediated
MMP activation may be a signal of prostate cancer progression
Buommino et al., Arch Dermatol Res 2012
(Psoriasis) :
Interestingly,
MMP-9 expression can be
enhanced also by
osteopontin (OPN) , a glycosylated protein whose levels are increased in skin and peripheral blood mononuclear cells ( PBMC ) of psoriasis patients
Tan et al., Lab Invest 2013
(Fibrosis...) :
Moreover,
MMP-9 inhibition
caused a significant reduction in MMP-9 cleaved
osteopontin and macrophage infiltration in UUO kidney