Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Liu et al., Mol Cell Biochem 2001 : It suggests that gp130 activate MAPK p42/44 and gp190 indirectly regulate its expression and function
Sun et al., Biochem Biophys Res Commun 2002 : Stimulation of gp130 on hippocampal neurons resulted in tyrosine phosphorylation of STAT3 and activation of p42 and p44 MAP kinases
Fahmi et al., Cell Signal 2013 (Hypertrophy...) : p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of JAK/STAT activation