Gene interactions and pathways from curated databases and text-mining

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CXCR4 — IL5

Text-mined interactions from Literome

Nagase et al., Int Arch Allergy Immunol 2001 (Hypersensitivity) : CXCR4 expression was completely attenuated by IL-4 and IL-5 and upregulated by IFN-gamma and dexamethasone, while CCR3 expression was only marginally affected
Iikura et al., J Leukoc Biol 2001 : IL-5 , GM-CSF, and IL-4 also down-regulated CXCR4 expression
Wilson et al., Infect Immun 1995 (Leishmaniasis, Visceral) : Recombinant Lcr1 , cloned adjacent to polyhistidine and purified on a nickel affinity column, stimulated gamma interferon but not interleukin-4 (IL-4), IL-5 , or IL-10 secretion by T-cell enriched splenocytes from either susceptible or resistant mice during L. chagasi infection