Gene interactions and pathways from curated databases and text-mining

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IL6 — LCN2

Text-mined interactions from Literome

Cowland et al., J Immunol 2003 : IL-1beta induces a > 10-fold up-regulation of NGAL expression in the type II pneumocyte derived cell line A549 cells, whereas TNF-alpha, IL-6 , and LPS had no effect
Lee et al., Nephron. Experimental nephrology 2012 (Acute Kidney Injury) : Surprisingly, in direct response to exogenous IL-6 , podocytes produce lipocalin-2/neutrophil gelatinase associated lipocalin ( Lcn2/Ngal ) ... Intense Lcn2/Ngal expression is also observed in IL-6 knockout mice, suggesting that while IL-6 may be sufficient to induce glomerular Lcn2/Ngal expression, it is not essential
Auguet et al., Exp Clin Endocrinol Diabetes 2013 (Fatty Liver...) : LCN2 expression was induced by TNFa, IL6 and resistin.Liver LCN2 is related to NAFLD in severely obese women