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IL6 — LCN2
Text-mined interactions from Literome
Cowland et al., J Immunol 2003
:
IL-1beta
induces a > 10-fold up-regulation of
NGAL expression in the type II pneumocyte derived cell line A549 cells, whereas TNF-alpha,
IL-6 , and LPS had no effect
Lee et al., Nephron. Experimental nephrology 2012
(Acute Kidney Injury) :
Surprisingly, in direct
response to exogenous
IL-6 , podocytes produce lipocalin-2/neutrophil gelatinase associated
lipocalin ( Lcn2/Ngal ) ... Intense Lcn2/Ngal expression is also observed in IL-6 knockout mice, suggesting that while
IL-6 may be
sufficient to induce glomerular
Lcn2/Ngal expression, it is not essential
Auguet et al., Exp Clin Endocrinol Diabetes 2013
(Fatty Liver...) :
LCN2 expression was
induced by TNFa,
IL6 and resistin.Liver LCN2 is related to NAFLD in severely obese women