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BMP2 — MYC

Text-mined interactions from Literome

Hu et al., Development 2005 (Kidney Diseases) : Here, we report enhanced interactions between a molecular complex consisting of Smad1, beta-catenin and Tcf4 and adjacent Tcf- and Smad binding regions located within the Myc promoter in TgAlk3QD dysplastic renal tissue, and Bmp dependent cooperative control of Myc transcription by Smad1, beta-catenin and Tcf4 ... In collecting duct cells that express luciferase under the control of the 1490 nucleotide Myc genomic region, Bmp2 dependent stimulation of Myc transcription was dependent on contributions by each of Tcf4, beta-catenin and Smad1
Lee et al., Cancer Res 2010 (Colorectal Neoplasms) : We show that upregulation of RUNX3 by BMP reduces c-Myc expression