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PCNA — PDGFB
Text-mined interactions from Literome
Sharma et al., Am J Physiol 1999
:
The eNOS transfer significantly inhibited ( P < 0.05 )
PDGF-BB induced
proliferating cell nuclear antigen ( PCNA ) and cyclin A expression in VSM cells compared with cells transfected with the control vector
Sanz-González et al., Biochem Biophys Res Commun 2004
:
STI571 abrogates
PDGF-BB dependent cyclin D1 and
cyclin A protein expression and inhibits transcriptional activation of reporter genes driven by the human cyclin A gene promoter ... We also found that STI571 abrogates
PDGF-BB dependent activation of extracellular regulated kinase 1 and 2 ( ERK1/2 ), and forced activation of these factors
impaired STI571 dependent inhibition of both
cyclin A promoter activity and SMC proliferation
Pan et al., Biochem Cell Biol 2007
:
Our results revealed that
PDGF-BB significantly
increased the expressions of TGF-beta1 and
PCNA , and the increase in PCNA can be partially inhibited by neutralizing anti-TGF-beta1 antibody ... These findings suggest that
PDGF-BB promotes
PCNA expression in VSMCs partially through TGF-beta1 overexpression, and that the TGF-beta signalling system involves the molecular mechanism of PDGF-BB in VSMCs
Karpurapu et al., J Biol Chem 2008
(Carotid Stenosis) :
Inhibition of nuclear factors of activated T cell ( NFAT ) activation by cyclosporin A ( CsA ) and VIVIT suppressed
PDGF-BB induced
cyclin A expression and CDK2 activity, resulting in blockade of VSMC in the G ( 1 ) phase
Xu et al., Clin Exp Pharmacol Physiol 2011
:
In addition, TSG significantly inhibited
PDGF-BB induced phosphorylation of Rb and the expression of cyclin D1, CDK4, cyclin E, CDK2 and
PCNA
Liu et al., Mol Cell Biochem 2011
:
Berberine and DHEAS decreased the expression of CDK2, CDK4,
PCNA , cyclin D1, and cyclin E, which was
induced by
PDGF-BB