Ree et al., Oncogene 2003
(Breast Neoplasms...) :
We found that cell cycle arrest at the G2/M boundary after ionizing radiation ( IR ) of breast carcinoma cells may involve repression of the gene for Plk1 , PLK, mediated by the tumor-suppressor protein BRCA1 Sankaran et al., Cancer Res 2007
:
We show that Aurora-A kinase modulates the BRCA1 inhibition of centrosome function by decreasing the E3 ubiquitin ligase activity of BRCA1