Gene interactions and pathways from curated databases and text-mining

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NOTCH1 — SOX9

Text-mined interactions from Literome

Muto et al., Exp Eye Res 2009 : Using an activated form of Notch and the gamma-secretase inhibitor DAPT, we also found that Notch signaling regulates the transcription of Sox8 and Sox9
Genethliou et al., Biochem Biophys Res Commun 2009 : We show that, SOX1 expression in the vSC is regulated by PAX6, NKX2.2 and Notch signalling in a domain-specific manner
Martini et al., Stem Cells 2013 : Transient or continuous activation of Notch1 during neuroectodermal differentiation led to upregulation of Sox9 expression ... Knockdown of the Notch1 induced Sox9 expression reversed Notch1 induced astroglial cell differentiation, increase in neural stem cells, and the decrease in neurons, whereas the Notch1 effects on NC development were hardly affected by knockdown of Sox9 expression