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BCL10 — EGF

Text-mined interactions from Literome

Fabregat et al., Hepatology 2000 : PI 3-kinase inhibitors completely block the protective effect of EGF on TGF-beta induced bcl-x ( L ) down-regulation
Cui et al., Mol Reprod Dev 2003 : Furthermore, semi-quantitative reverse transcriptase-polymerase chain reaction ( RT-PCR ) revealed that EGF enhanced the mRNA expression of Bcl-xL in the presence of 0.4 % BSA but BSA and EGF alone had no effect ... These results suggest that EGF and BSA synergistically enhance Bcl-xL gene expression, which may result in a net increase in cell number in porcine presumptive diploid parthenotes developing in vitro
Takeuchi et al., FEBS J 2006 (Adenocarcinoma...) : EGF increased the expression of the Bcl-X ( L ) protein, an antiapoptotic member of the Bcl-2 family, but not that of other anti ( Bcl-2 ) or proapoptotic ( Bad and Bax ) protein members ... Pretreatment of the cells with PD98059, an inhibitor of MAP kinase kinase, inhibited the EGF induced c-Fos and c-Jun expression, AP1 DNA binding, Bcl-X ( L ) expression, and the resistance against ADR induced apoptosis, suggesting that EGF transmitted the antiapoptotic signal in such a way that it activated AP1 via a MAP kinase signaling pathway ... TMK-1 cells stably transfected with TAM67, c-Jun dominant negative mutant, did not display EGF induced Bcl-X ( L ) expression or resistance against ADR induced apoptosis
Jin et al., J Cell Physiol 2007 : Epidermal growth factor (EGF) induces Bad phosphorylation at Ser112 via mitogen activated protein kinase ( MAPK ), impairing its binding to Bcl-2 and Bcl-xL and interfering with their anti-apoptotic functions
Karl et al., Cell Death Differ 2007 : Here, we showed that epidermal growth factor (EGF) induces in vitro capillary sprouting and Bcl-x ( L ) expression in primary endothelial cells