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IFNG — SELE
Text-mined interactions from Literome
Eppihimer et al., Shock 1999
(Shock, Septic) :
Role of tumor necrosis factor and
interferon gamma in endotoxin induced
E-selectin expression ... Although
IFN-gamma deficiency
had no effect on
E-selectin expression in other tissues, administration of TN3 to endotoxin challenged, IFN-gamma-deficient mice significantly reduced E-selectin expression to levels observed in endotoxin challenged, wild-type mice that received TN3
Murakami et al., Microvasc Res 2001
:
TNF-alpha induced the expression of E-selectin on all three kinds of endothelial cells, but
IFN-gamma had no effect on
E-selectin expression
Teo et al., The AAPS journal 2005
(Multiple Myeloma...) :
They
induce an IL-2 mediated primary T cell proliferation with a concomitant increase in
IFN-gamma production and decrease the density of TNF-alpha induced cell surface adhesion molecules ICAM-1, VCAM-1, and
E-selectin on human umbilical vein endothelial cells
Thornhill et al., J Immunol 1990
:
In contrast,
IFN-gamma stimulation increases EC binding of T cells but not PMN and
enhances ICAM-1 expression but not
ELAM-1 or 1.4C3 Ag expression
Doukas et al., J Immunol 1990
:
IFN-gamma , which by itself increases EC class I MHC and ICAM-1 but does not
induce ELAM-1 expression, has been found to act synergistically with TNF to increase class I expression ... IFN-gamma increases TNF induced ELAM-1 expression such that a greater number of EC express
ELAM-1 at both 4 and 24 h in the
presence of
IFN-gamma plus TNF compared to cultures treated with TNF alone, although the maximal level of surface expression on individual cells is not increased
Leeuwenberg et al., J Immunol 1990
:
IFN-gamma regulates the expression of the adhesion molecule
ELAM-1 and IL-6 production by human endothelial cells in vitro ... Whereas
IFN-gamma per se did not
induce expression of
ELAM-1 , it enhanced and prolonged the expression of ELAM-1
Tabibzadeh et al., J Clin Endocrinol Metab 1994
:
Expression of
E-selectin on endothelial cells was
induced only by IL-1 alpha, not by
IFN gamma or TNF alpha
Lee et al., J Dermatol Sci 1995
:
We have demonstrated that stimulation of HDMEC with IL-1 alpha or TNF alpha leads to transient E-selectin induction which disappears after 48 h, but stimulation of HDMEC with
IFN-gamma resulted in delayed
E-selectin induction which was seen at 48 h of incubation and persisted until 72 h after stimulation
Scholz et al., Transplantation 1996
(Cytomegalovirus Infections) :
Whereas oxidative stress alone did not modulate any surface molecule expression, the
IFN-gamma mediated expression of HLA-ABC and HLA-DR and the IL-1 mediated expression of ICAM-1, but not of
ELAM-1 and VCAM-1 ( IL-1 + TNF-alpha ), was amplified
Henseleit et al., J Pathol 1996
(Dermatitis, Allergic Contact...) :
LPS and tumour necrosis factor-alpha (TNF-alpha), but not interleukin-4 (IL-4) or
interferon-gamma (IFN-gamma) ,
induced a transient expression of
E-selectin , both when injected in vivo and when added to endothelial cell lines in vitro
Savage et al., J Pathol 1997
:
Expression of
E-selectin on glomerular endothelial cells ( ECs ) was
induced by interleukin-1 (IL-1), tumour necrosis factor (TNF),
interferon-gamma (IFN-gamma) and granulocyte/ macrophage-colony stimulating factor ( GM-CSF ) ; this induction was inhibited by transforming growth factor beta ( TGF beta ) and by IL-4
Mizutani et al., Arch Dermatol 1997
(Dermatitis, Allergic Contact...) :
While
interferon gamma strongly
induced E-selectin expression on endothelial cells in normal skin, it failed to induce endothelial E-selectin expression in the NA
Okada et al., Ann Med Interne (Paris) 1997
:
IFN gamma did not
cause any changes in the expression of
ELAM-1 , VCAM-1, and ICAM-1
Strindhall et al., Scand J Immunol 1997
:
The aim of the present study was to investigate if altered protein glycosylation could explain the
IFN-gamma induced persistent surface expression of
E-selectin ... When HUVEC were incubated with monesin, a potent inhibitor of late Golgi function, together with both TNF-alpha and IFN-gamma, the additive
effect of
IFN-gamma on
E-selectin expression was almost abolished
Shen et al., J Virol 1997
:
TNF-alpha significantly
enhanced WNV induced increases in
E-selectin , P-selectin, ICAM-1, and VCAM-1 expression, while
IFN-gamma enhanced WNV induced ICAM-1 expression