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LIF — MYC

Text-mined interactions from Literome

Spinsanti et al., J Neurochem 2006 : The selective mGlu5 receptor antagonist, 2-methyl-6- ( phenylenthynyl ) pyridine ( MPEP ; 1 mum ), reduced the increase in c-Myc protein levels induced by LIF by enhancing c-Myc ubiquitination ... We conclude that endogenous activation of mGlu5 receptors sustains the increase in c-Myc induced by LIF in embryonic stem cells by inhibiting both glycogen synthase kinase-3beta and PI-3-K, both effects resulting from the activation of PKC
Lee et al., J Lipid Res 2010 : However, caveolin-1 siRNA did not influence LIF induced phosphorylation of STAT3 and Akt, and expression of c-Myc
David et al., Am J Pathol 2012 (Bone Neoplasms...) : Knockdown experiments demonstrated that growth induction by OSM depends on both types I [leukemia inhibitory factor receptor ( LIFR ) ] and II [OSM receptor ( OSMR ) ] receptors, high STAT3 activation, and induction of MYC to a high expression level
Buono et al., Dev Neurosci 2012 : Finally, we show that LIF increases the expression of the core transcription factors : Klf4, Fbx15, Nanog, Sox2 and c-Myc