Gene interactions and pathways from curated databases and text-mining

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FGF1 — IL2

Text-mined interactions from Literome

Byrd et al., J Immunol 1999 : Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor bearing Jurkat T cells
Thomas et al., Arthritis Rheum 2000 : Tumor necrosis factor alpha, interleukin-6 , and epidermal growth factor did not increase aFGF expression in vitro ; in contrast, transforming growth factor beta1 ( TGFbeta1 ) was found to markedly increase aFGF production by cultured synovial cells
Chandrasekhar et al., J Cell Physiol 1989 : Induction of interleukin-1 receptors on chondrocytes by fibroblast growth factor : a possible mechanism for modulation of interleukin-1 activity
Iwamoto et al., Immunol Lett 1989 : Furthermore, interleukin 1 (IL-1) suppressed by 50-60 % the incorporation of [ 3H ] thymidine into DNA in high density chondrocyte cultures on plastic dishes in the presence of 10 % serum or fibroblast growth factor , although it increased twofold this incorporation in 0.3 % serum alone
Norioka et al., Jpn J Cancer Res 1994 (Neovascularization, Pathologic) : Interaction of interleukin-1 and interferon-gamma on fibroblast growth factor induced angiogenesis
Shi et al., J Immunol 1997 : IL-2 also induced apoptosis in normal IL-2-responsive human T cell blasts in the absence of serum, and furthermore, epidermal growth factor and fibroblast growth factor induced increased rates of apoptosis in fibroblasts in the absence of serum, suggesting that cytokine induced apoptosis in the absence of serum survival factors might represent an important biologic phenomenon