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HDAC1 — IL1B

Text-mined interactions from Literome

Carta et al., Blood 2006 (Calcium Signaling) : In the present study, we investigated the effects of 2 HDAC inhibitors on IL-1beta secretion : suberoylanilide hydroxamic acid and a newly developed hydroxamic acid derived compound ITF2357 ... These HDAC inhibitors do not affect the synthesis or intracellular localization of IL-1beta but both strongly reduce the levels of extracellular IL-1beta by preventing the exocytosis of IL-1beta containing secretory lysosomes
Yoshikawa et al., Arch Otolaryngol Head Neck Surg 2006 (Cholesteatoma, Middle Ear) : The messenger RNA expressions of LARC ( liver and activation regulated chemokine ), GMCSF ( granulocyte-macrophage colony stimulating factor ), epiregulin, ICAM1 ( intercellular adhesion molecule 1 ), and TGFA ( transforming growth factor alpha ) were more strongly up-regulated by IL-1alpha and/or IL-1beta in MECF than in SF, suggesting that these fibroblasts derived from different tissues retained their typical gene expression profiles
Wang et al., Growth Factors 2009 : To investigate the functional involvement of HDACs in the signaling pathway of FGF2 and IL-1beta, we examined the effects of HDAC inhibition on activities of FGF2 or IL-1beta on gene expression of MMP-1, MMP-3, MMP-13, a disintegrin and metalloproteinase with thrombospondin motifs-5 ( ADAMTS5 ), collagen type II, and aggrecan