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HLA-DRB1 — TNF

Text-mined interactions from Literome

Termeer et al., J Leukoc Biol 2001 : In this system, addition of anti-CD44s mAbs abrogated DC-cluster formation, thereby inhibiting further maturation, as shown by a reduced TNF-alpha production and inhibition of CD154 induced MHC class II up-regulation
Kim et al., Diabetologia 2002 (Insulinoma...) : TNFalpha alone did not induce MHC class II expression, but enhanced IFN gamma induced MHC class II expression ... IFN gamma and TNFalpha synergistically induced MHC class II expression on insulinoma cells through the induction of CIITA ; nicotinamide reduced the expression of cytokine induced MHC class II expression on insulinoma cells through its effect on CIITA expression ; and the preventive effect of nicotimamide on Type I ( insulin dependent ) diabetes mellitus is probably due to its effect of MHC class II expression rather than that on islet cell apoptosis
Annunziata et al., J Neuroimmunol 2002 : In a dose dependent manner, spantide completely neutralized increased permeability induced by TNF-alpha and IFN-gamma and expression of MHC class II molecule induced by IFN-gamma and prevented associated cell morphological changes as revealed by scanning electron microscope
Spurzem et al., J Lab Clin Med 1992 : With an in vitro system of bovine bronchial epithelial cells, we evaluated the effects of both a lymphokine containing supernatant and recombinant tumor necrosis factor-alpha on MHC class II expression ... Tumor necrosis factor-alpha had no effect on MHC class II surface antigen expression
Nascimento et al., J Ethnopharmacol 2006 : Our results demonstrate that BM injected once ip in mice at 10 and 20 mg/kg increased the cellular influx to the peritoneal cavity, the MHC class II expression and the spreading ability, and also induced the production of NO, TNF and H ( 2 ) O ( 2 )
Deja et al., Mediators Inflamm 2006 (Diabetes Mellitus, Type 1...) : Is the association between TNF-alpha-308 A allele and DMT1 independent of HLA-DRB1 , DQB1 alleles ?
Robinson et al., Ann N Y Acad Sci 2007 : Activation of TNFR1 or DR5 by TNF-alpha or TRAIL may regulate osteoblast connectivity, which is important to bone turnover
Watanabe et al., J Immunol 1991 (Leukemia, Promyelocytic, Acute) : In the present studies, the effect of TNF-alpha on IFN-gamma induced MHC class II expression was tested in various cell lines
Nguyen et al., Clin Immunol 2009 (Lupus Nephritis) : In vitro, expression of TRAIL, DR4 and DR5 on primary proximal tubular epithelial cells ( PTEC ) was induced by TNFalpha and IFNgamma
Detmar et al., J Invest Dermatol 1990 : We investigated the effects of recombinant human tumor necrosis factor-alpha (TNF) on cell proliferation and on expression of MHC class II antigens and intercellular adhesion molecule ICAM-1 in human dermal microvascular endothelial cells ( HDMEC ) derived from human foreskin
Dittmar et al., Immunol Invest 2009 (Genetic Predisposition to Disease...) : The association of TNF-alpha ; -308*A with PGA might be directly or indirectly due to the association with HLA-DRB1*03
Trede et al., J Immunol 1991 : Transcriptional activation of IL-1 beta and tumor necrosis factor-alpha genes by MHC class II ligands
Keller et al., J Biol Chem 2011 (Inflammation...) : TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells ... Furthermore, TNF-a augmented surface expression of MHC class II molecules in interferon-? ( IFN-? ) -treated myoblasts ... The synergistic effect of TNF-a and IFN-? on the induction of MHC class II surface expression was not reflected by higher intracellular human leukocyte antigen ( HLA ) -DR levels and was reversed by macroautophagy inhibition, suggesting that TNF-a facilitates antigen processing via macroautophagy for more efficient MHC class II loading ... These findings establish a mechanism through which TNF-a regulates both macroautophagy and MHC class II expression and suggest that macroautophagy mediated antigen presentation contributes to the immunological environment of the inflamed human skeletal muscle
Helbig et al., Graefes Arch Clin Exp Ophthalmol 1990 : Tumor necrosis factor increased IFN-G induced MHC class II expression
Kingston et al., Eur J Immunol 1989 : Schwann cells co-cultured with stimulated T cells and antigen express major histocompatibility complex ( MHC) class II determinants without interferon-gamma pretreatment : synergistic effects of interferon-gamma and tumor necrosis factor on MHC class II induction
Willheim et al., Eur J Immunol 1995 (Leukemia, Promyelocytic, Acute) : In contrast to the parental U937 cell line, only tumor necrosis factor (TNF)-alpha , and not interferon (IFN)-gamma induces the expression of MHC class II antigens on C119/9 cells, and paradoxically, this induction was inhibited almost completely by IFN-gamma
Sicher et al., J Immunol 1995 : Studies with a neutralizing anti-TNF-alpha Ab, however, indicate that LPS augmentation of MHC class II did not require TNF-alpha
Jasiński et al., J Clin Immunol 1995 : Isotype-specific regulation of MHC class II gene expression in human monocytes by exogenous and endogenous tumor necrosis factor
Espel et al., Eur J Immunol 1996 : Taken together, our data indicate that TNF-alpha expression is tightly regulated by MHC class II ligands, both at the transcriptional and translational levels
Hogaboam et al., Gastroenterology 1997 : When added with 100 U/mL IFN-gamma, TNF-alpha enhanced MHC class II and ICAM-1 expression on ISMCs and T-cell proliferation
Jakob et al., J Immunol 1998 : Flow cytometry of FSDDC-A revealed that IL-1, TNF-alpha , and LPS induced increased expression of MHC class II , CD40, and CD86 and decreased E-cadherin expression that was temporally related to dissociation of aggregates
Sheikh et al., Cancer Res 1998 : TNF-alpha , a nongenotoxic cytokine, also induced the expression of KILLER/DR5 in a number of cancer cell lines, irrespective of p53 status
Ljunggren et al., J Reprod Immunol 1998 : TNF-alpha and TGF-beta1 inhibited the IFN-gamma induced MHC class II expression