UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

BioCarta eukaryotic protein translation: 40s Ribosome subunit/RNA strand complex () → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
BioCarta eukaryotic protein translation: eIF3 (EIF3S10) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
BioCarta eukaryotic protein translation: eIF1 (EIF1) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, activates)
BioCarta eukaryotic protein translation: 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) → EIF-2 complex (EIF2S1-EIF2S2-EIF2S3) (modification, collaborate)
BioCarta eukaryotic protein translation: 43s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
BioCarta eukaryotic protein translation: 43s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3) → eIF4F/mRNA complex (EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
BioCarta eukaryotic protein translation: 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) → eIF4F/mRNA complex (EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)

Studies that report less than 10 interactions are marked with *

IRef Hprd Interaction: EIF2S2 — EIF4G2 (in vivo) Lee et al., EMBO J 2006 *
IRef Hprd Interaction: EIF2S2 — EIF4G2 (in vitro) Lee et al., EMBO J 2006 *
IRef Intact Interaction: EIF2S2 — EIF4G2 (physical association, anti tag coimmunoprecipitation) Lee et al., EMBO J 2006 *
IRef Intact Interaction: EIF2S2 — EIF4G2 (physical association, pull down) Lee et al., EMBO J 2006 *
IRef Intact Interaction: EIF2S2 — EIF4G2 (physical association, anti bait coimmunoprecipitation) Lee et al., EMBO J 2006 *
IRef Intact Interaction: Complex of EIF2S2-EIF2S1-EIF4G2 (colocalization, cosedimentation through density gradient) Lee et al., EMBO J 2006 *