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LPA — MET

Text-mined interactions from Literome

Shida et al., Exp Cell Res 2004 (Stomach Neoplasms) : Immunoprecipitation analysis revealed that LPA induced transient tyrosine phosphorylation of c-Met in LPA2 expressing cells, which suggests that the transactivation of c-Met by LPA causes a cooperative migratory response with HGF to these cells
Shida et al., World J Gastroenterol 2005 (Colonic Neoplasms) : To examine whether lysophosphatidic acid (LPA) induces phosphorylation of c-Met and epidermal growth factor receptor (EGFR), both of which have been proposed as prognostic markers of colorectal cancer, and whether LPA induces cyclooxygenase-2 (COX-2) expression in human colon cancer cells
Yamashita et al., J Surg Oncol 2006 (Adenocarcinoma...) : Since LPA can transactivate HGF receptor ( c-Met ) as well as EGF-receptor, LPA may promote the progression of gastric cancer in diffuse-type with high expression of c-Met
Zhao et al., Cell Signal 2007 : Treatment of HBEpCs with LPA induced c-Met serine phosphorylation and redistribution to plasma membrane, while treatment with HGF induced c-Met internalization ... Overexpression of dominant negative ( Dn ) -PKC delta or pretreatment with Rottlerin or Pertussis toxin ( PTx ) attenuated LPA induced c-Met serine phosphorylation and redistribution
Zhao et al., Am J Physiol Lung Cell Mol Physiol 2013 : We have previously shown that lysophosphatidic acid (LPA) induced a decrease in c-Met activation via serine phosphorylation of c-Met at cell-cell contacts