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HMGB1 — NOS2
Text-mined interactions from Literome
Carvajal et al., Crit Care Med 2002
(Inflammation...) :
We will review the mechanisms by which HMG-I/Y proteins regulate gene transcription, give an overview of selected genes regulated by HMG-I/Y, summarize the potential roles of these genes in critical illnesses, and provide more detailed information about the
role of
HMG-I/Y in the regulation of
nitric oxide synthase-2 during an inflammatory response, such as endotoxemia/sepsis
Ivanov et al., Blood 2007
:
Loss of
HMGB1 leads to a defect in the IL-6, IL-12, TNFalpha, and
iNOS response to CpG-ODN