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IL1B — MYLIP
Text-mined interactions from Literome
Stanczyk et al., Arthritis Rheum 2008
(Arthritis, Rheumatoid) :
Constitutive expression of both miR-155 and miR-146a was higher in RASFs than in those from patients with osteoarthritis ( OA ), and expression of
miR-155 could be further
induced by TNFalpha,
interleukin-1beta , lipopolysaccharide, poly ( I-C ), and bacterial lipoprotein
Jones et al., Osteoarthritis Cartilage 2009
(Osteoarthritis, Knee) :
Over-expression of
miR-9 , miR-98 or miR-146 in isolated human chondrocytes
reduced interleukin-1 beta (IL-1 beta) induced TNF-alpha production
Yamasaki et al., Arthritis Rheum 2009
(Osteoarthritis) :
This study shows that
miR-146 is intensely expressed in low-grade OA cartilage and that its expression is
induced by stimulation of
IL-1beta
Miyaki et al., Arthritis Rheum 2009
(Osteoarthritis, Knee) :
We tested the
effects of
interleukin-1beta (IL-1beta) on
miR-140 expression ... The reduction in
miR-140 expression in OA cartilage and in
response to
IL-1beta may contribute to the abnormal gene expression pattern characteristic of OA
Roggli et al., Diabetes 2010
(Inflammation) :
We found that
IL-1beta and TNF-alpha
induce the expression of miR-21, miR-34a, and
miR-146a both in MIN6 cells and human pancreatic islets
Akhtar et al., Arthritis Rheum 2010
(Osteoarthritis) :
Furthermore,
IL-1beta induced activation of signal transduction pathways associated with the expression of MMP-13
down-regulated the expression of
miR-27b
Larner-Svensson et al., Respir Res 2010
:
Functional studies indicated that
IL-1beta induced
miR-146a expression does not negatively regulate IL-6 and IL-8 release or basal proliferation ... We have shown that
IL-1beta induced
miR-146a expression in HASM and that this was regulated at the transcriptional level by NF-kappaB and at the post-transcriptional level by the MEK-1/2 and JNK-1/2