Gene interactions and pathways from curated databases and text-mining

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PTGS2 — S1PR3

Text-mined interactions from Literome

Kim et al., J Biol Chem 2003 : Transfection of S1P1 or S1P3 but not of S1P2 antisense oligonucleotide inhibited S1P induced COX-2 expression and PGE2 production in WISH cells, indicating the involvements of S1P1 and S1P3 in the processes
Ki et al., J Biol Chem 2007 : Experiments using siRNAs specifically directed against S1P ( 1-5 ) showed that S1P ( 1 ), S1P(3) , and S1P(5) are necessary for the full activation of COX-2 induction