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MAPK6 — SYK

Text-mined interactions from Literome

Canobbio et al., Thromb Haemost 2004 : How-ever, phosphorylation of p38MAPK was prevented by the tyro-sine kinase Syk inhibitor piceatannol
Hayashi et al., J Biol Chem 2004 : It also elicited tyrosine phosphorylation of DAP12, Syk, and SLP-76, and a Syk inhibitor blocked the promotion of phagocytosis and activation of MAPK by SIRPbeta
Takada et al., J Immunol 2004 : Overall, our results demonstrate that Syk activation plays an essential role in TNF induced activation of JNK, p38 MAPK, p44/p42 MAPK , NF-kappaB, and apoptosis
Ulanova et al., Biochem Biophys Res Commun 2006 : Inhibition of Syk down-regulated TNF induced p38 and p44/42 MAPK phosphorylation and nuclear translocation of p65 NF-kappaB
Wang et al., J Immunol 2006 : Syk is downstream of intercellular adhesion molecule-1 and mediates human rhinovirus activation of p38 MAPK in airway epithelial cells
Lau et al., J Immunol 2008 : We recently demonstrated the Syk tyrosine kinase to be an important mediator of HRV-ICAM-1 signaling : Syk regulates replication independent p38 MAPK activation and IL-8 expression
Honda et al., J Biol Chem 1997 : The onsets of the series of events including tyrosyl phosphorylation of Syk , mitogen activated protein ( MAP ) kinase activation , elevation of intracellular calcium concentration ( [ Ca2+ ] i ), and histamine release were all stepwisely delayed in Csk expressing cells and in mCsk expressing cells
Jiang et al., J Exp Med 1998 : However, BCR mediated p38 MAPK activation was abolished in Lyn/Syk double deficient cells, demonstrating that either Lyn or Syk alone may be sufficient to activate p38 MAPK