Gene interactions and pathways from curated databases and text-mining

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EGFR — LILRB1

Text-mined interactions from Literome

Kefas et al., Cancer Res 2008 (Brain Neoplasms...) : miR-7 potently suppressed epidermal growth factor receptor expression, and furthermore it independently inhibited the Akt pathway via targeting upstream regulators
Duex et al., J Biol Chem 2011 (Neoplasms) : Given earlier evidence of EGFR regulation by the microRNA miR-7 , we assessed whether miR-7 mediates Usp18 siRNA effects
Lee et al., Radiother Oncol 2011 : Ectopic overexpression of miR-7 attenuated EGFR and Akt expression and radiosensitized SQ20B squamous cell carcinoma of the larynx, MDA-MB-468 breast cancer cells, A549 lung carcinoma cells, and U251 and U87 malignant glioma cells
Kalinowski et al., PloS one 2012 (Head and Neck Neoplasms) : Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7
Masuda et al., Journal of translational medicine 2012 (Breast Neoplasms) : Transfection of miR-7 significantly suppressed EGFR mRNA levels in MCF-7 cells
Wang et al., Neoplasma 2013 (Brain Neoplasms...) : Western blotting analysis was performed, which indicated that miR-7 directly inhibited epidermal growth factor receptor (EGFR) and further antagonized the downstream protein kinases including ERK, Akt and Stat3
Chen et al., Evidence-based complementary and alternative medicine : eCAM 2013 : Our data showed the miR-7 dependent EGFR suppression by HBx, supporting an inhibitory role of HBx in the cell growth of HCC