◀ Back to CDH1

CDH1 — ESR1

Text-mined interactions from Literome

Park et al., Mol Endocrinol 2008 (Ovarian Neoplasms) : We also showed that ERbeta had an opposing action on ERalpha because the presence of ERbeta completely inhibited the EMT and down-regulation of E-cadherin induced by ERalpha
Helguero et al., Cancer Res 2008 : Ligand activation of ERalpha induced E-cadherin extracellular shedding and internalization only in the absence of ERbeta, followed by lysosomal degradation
Cardamone et al., Proc Natl Acad Sci U S A 2009 (Breast Neoplasms) : Similarly, transfection of ERalpha , in the absence of ligands, was sufficient to restore E-cadherin transcription in both sfRON-T47D and other ERalpha-, E-cadherin negative cells
Ye et al., Oncogene 2010 (Breast Neoplasms) : ERalpha signaling through slug regulates E-cadherin and EMT ... We have noted that human breast cancers exhibit a strong direct correlation between ERalpha and E-cadherin expression by immunohistochemistry, suggesting that ERalpha signaling might regulate E-cadherin and implying that this regulation might influence epithelial-mesenchymal transition (EMT) and tumor progression ... Our findings indicate that ERalpha signaling through slug regulates E-cadherin and EMT