Gene interactions and pathways from curated databases and text-mining

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EPHB2 — IRAK3

Text-mined interactions from Literome

Su et al., Cell Signal 2007 : Furthermore, using bone marrow derived macrophages ( BMDM ) from wild type, IRAK1 ( -/- ), and IRAK-M ( -/- ) mice, we have herein demonstrated that IRAK-M selectively attenuates bacterial lipopeptide Pam ( 3 ) CSK ( 4 ) -induced p38 activation, but not ERK or JNK
Zacharioudaki et al., J Immunol 2009 : Activation of ERK1/2 via Tpl2 appeared necessary for the induction of IRAK-M because gAd did not induce IRAK-M in Tpl2 ( -/- ) macrophages or in macrophages pretreated with the MEK1/2 inhibitor UO126
Banerjee et al., Carcinogenesis 2011 (Neoplasms, Experimental) : Moreover, ERK-1/2 MAPK activation resulted in enhanced IRAK M induction in TAM, a specific inhibitor of MyD88 pathway