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EPHB2 — IRAK3
Text-mined interactions from Literome
Su et al., Cell Signal 2007
:
Furthermore, using bone marrow derived macrophages ( BMDM ) from wild type, IRAK1 ( -/- ), and IRAK-M ( -/- ) mice, we have herein demonstrated that
IRAK-M selectively
attenuates bacterial lipopeptide Pam ( 3 ) CSK ( 4 ) -induced p38 activation, but not
ERK or JNK
Zacharioudaki et al., J Immunol 2009
:
Activation of
ERK1/2 via Tpl2 appeared
necessary for the induction of
IRAK-M because gAd did not induce IRAK-M in Tpl2 ( -/- ) macrophages or in macrophages pretreated with the MEK1/2 inhibitor UO126
Banerjee et al., Carcinogenesis 2011
(Neoplasms, Experimental) :
Moreover,
ERK-1/2 MAPK activation
resulted in enhanced
IRAK M induction in TAM, a specific inhibitor of MyD88 pathway