◀ Back to NOTCH4
NOTCH4 — PIEZO1
Text-mined interactions from Literome
Zhang et al., Dev Biol 2007
:
It was also shown that
Notch signaling negatively
regulates mib expression in a Su ( H ) -dependent manner, forming a negative feedback loop in modulating Notch activation
Yoon et al., Mol Cell Biol 2008
:
We previously reported that
Mind bomb-1 (Mib1) regulates
Notch ligands in the Notch signal sending cells ( B. K. Koo, M. J. Yoon, K. J. Yoon, S. K. Im, Y. Y. Kim, C. H. Kim, P. G. Suh, Y. N. Jan, and Y. Y. Kong, PLoS ONE 2 : e1221, 2007 )
Jeong et al., PloS one 2012
:
Here, we observed that expression of
Mind bomb-1 (Mib1) , a critical
regulator of
Notch ligands for the activation of Notch signaling, increases gradually as precursor cells differentiate into DCs in mice ... Our results demonstrate that
Mib1 in DCs is
critical for the activation of
Notch signaling in CD4 ( + ) T cells, and Notch signaling reinforces Th2 differentiation, but is not required for the activation or proliferation of the CD4 ( + ) T cells
Yoon et al., Molecular brain 2012
:
These data suggest that
Mib1 mediated
Notch signaling is essential for long lasting synaptic plasticity and memory formation in the rodent hippocampus