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FASLG — TP53

Text-mined interactions from Literome

Embree-Ku et al., Toxicol Pathol 2002 (Disease Models, Animal...) : The FasL deficiency reduced the median time to death from 12.1 months in FasL +/+ p53 +/- mice to 9.6 months in FasL -/- p53 +/- mice, and led to a shift in tumor spectrum from predominantly sarcomas ( 63 % ) when FasL was present to a large number of lymphomas ( 76 % ) in FasL -/- p53 +/- mice
Atten et al., Invest New Drugs 2005 (Adenocarcinoma...) : SNU-1 cells respond to resveratrol treatment with up-regulation of both Fas and Fas-L proteins, whereas in KATO-III cells, with deleted p53 , only Fas-L is increased after resveratrol treatment
Kuo et al., Chem Biol Interact 2005 (Disease Models, Animal) : CS triggered activation of MAP kinase ( p38/JNK or ERK2 ) pathway, which led to Jun or p53 phosphorylation and FasL induction links Fas phosphorylation
Okazaki et al., J Cancer Res Clin Oncol 2007 (Disease Models, Animal...) : By Northern blot and Western blot analyses, we determined the effect of p53 on the FasL and Fas receptor expression
Koster et al., Cell death & disease 2011 (Testicular Neoplasms) : More specifically, our results indicate that p53 dependent induction of Fas membrane expression ( ~threefold ) and enhanced Fas/FasL interactions at the cell surface are important mechanisms of Nutlin-3 induced apoptosis in TC cells