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NFE2 — SFN

Text-mined interactions from Literome

Ping et al., Brain Res 2010 (Disease Models, Animal...) : Sulforaphane (SFN) , an isothiocyanate found in cruciferous vegetables, has cytoprotective effects against oxidative stress and its effect was mediated by NF-E2 related factor-2 (Nrf2) , a transcription factor, and heme oxygenase 1 (HO-1) which is one of Nrf2 downstream target genes
Xu et al., Anticancer Agents Med Chem 2012 (Neoplasms) : NF-E2- related factor-2(Nrf-2) , as well as mitogen activated protein kinase ( MAPK ), is regulated by SFN
Bai et al., J Mol Cell Cardiol 2013 (Diabetes Mellitus, Experimental...) : SFN up-regulated NFE2 related factor 2 (Nrf2) expression and transcription activity that was reflected by increased Nrf2 nuclear accumulation and phosphorylation as well as the mRNA and protein expression of Nrf2 downstream antioxidants