Oh et al., Proc Natl Acad Sci U S A 2000
:
The blood vessel defects in ALK1-deficient mice are reminiscent of mice lacking TGF-beta1, TGF-beta type II receptor ( TbetaR-II ), or endoglin, suggesting that ALK1 may mediate TGF-beta1 signal in endothelial cells
Velasco et al., J Cell Sci 2008
:
L- and S-endoglin differentially modulate TGFbeta1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts
Lee et al., Mol Biol Cell 2009
(Teratocarcinoma) :
Here, we report that although the transforming growth factor ( TGF ) -beta type III receptor ( TbetaRIII ) enhanced both ALK3 and ALK6 signaling, TbetaRIII more potently enhanced ALK6 mediated stimulation of the BMP-responsive promoters XVent2 and 3GC2, and up-regulation of the early response gene Smad6