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BCAR3 — RAC3
Text-mined interactions from Literome
Cai et al., Cancer Res 2003
(Breast Neoplasms...) :
AND-34/BCAR3 , a GDP exchange factor whose overexpression confers antiestrogen resistance,
activates Rac , PAK1, and the cyclin D1 promoter
Vanden Borre et al., Cell Signal 2011
:
Using R743A BCAR3, a point mutant that has lost the ability to bind p130Cas, we find that BCAR3-p130Cas complex formation is not required for
BCAR3 mediated anti-estrogen resistance,
Rac activation or discohesion of epithelial breast cancer cells