Gene interactions and pathways from curated databases and text-mining

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BCAR3 — RAC3

Text-mined interactions from Literome

Cai et al., Cancer Res 2003 (Breast Neoplasms...) : AND-34/BCAR3 , a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac , PAK1, and the cyclin D1 promoter
Vanden Borre et al., Cell Signal 2011 : Using R743A BCAR3, a point mutant that has lost the ability to bind p130Cas, we find that BCAR3-p130Cas complex formation is not required for BCAR3 mediated anti-estrogen resistance, Rac activation or discohesion of epithelial breast cancer cells