Deavall et al., Am J Physiol Gastrointest Liver Physiol 2000
(Neuroendocrine Tumors) :
We conclude that PACAP increases CCK gene expression via a cAMP mediated pathway involving CREB phosphorylation by protein kinase A and activation of a composite CRE/AP1 site
Hansen et al., Neuroreport 2004
(Neuroblastoma) :
We conclude that GSK-3beta regulates cAMP induced CCK transcription by reducing CREB binding to the CRE ( -80 ) element in the CCK promoter
de Lartigue et al., J Neurosci 2007
:
Using a CART promoter-luciferase reporter vector transfected into cultured vagal afferent neurons, we showed that CCK stimulation of CART transcription was mediated by activation of protein kinase C and cAMP response element binding protein ( CREB )